Monocytes and macrophages in atherogenesis

resistance training, interleukin-10, lymphocytes, monocytes, macrophages.

مقدمه: پرفشارخونی یکی از بیماری­های همراه با بیماری دیابت نوع 2 است که در بیشتر بیماران دیابتی نوع 2 دیده می‌شود. هدف از انجام این تحقیق بررسی اثر ورزش ایروبیک بر روی فشارخون زنان دیابتی نوع 2 است. روش پژوهش: تعداد 32 بیمار دیابتی نوع 2 که دارای فشارخون بالا بودند به صورت تصادفی به دو گروه تقسیم شدند: گروه ورزش ایروبیک (16 نفر) و گروه کنترل (بدون ورزش) (16 نفر)...

Role of Monocytes in Atherogenesis

Role of monocytes in atherogenesis.

This review focuses on the role of monocytes in the early phase of atherogenesis, before foam cell formation. An emerging consensus underscores the importance of the cellular inflammatory system in atherogenesis. Initiation of the process apparently hinges on accumulating low-density lipoproteins (LDL) undergoing oxidation and glycation, providing stimuli for the release of monocyte attracting ...

Adrenomedullin in monocytes and macrophages: possible involvement of macrophage-derived adrenomedullin in atherogenesis.

Macrophages secrete a variety of growth factors, cytokines and vasoactive peptides, which are related to the progression of atherosclerosis. Adrenomedullin (ADM) is a potent vasodilator peptide and inhibits proliferation and migration of vascular smooth muscle cells. In this study, we investigated the production and secretion of ADM by monocytes and macrophages by Northern blot analysis, RIA an...

Effect of Peganum Harmala Seeds Extract on Nitric Oxide in U937 Monocytes and Macrophages

Background and Aims: Nitric oxide (NO) has an essential role in inflammation and has been related to pathogenesis and the progress of numerous inflammatory-based diseases, including some cancers. Peganum harmala (P. harmala) is a medicinal plant used for the treatment of numerous diseases such as several infections. Also, anti-inflammatory effects of P. harmala extracts and its derivatives (har...